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DOD Awards Ology Vaccine Manufacturing Contract

CDMO to manufacture and test novel live attenuated tularemia vaccine candidate.

By: Contract Pharma

Contract Pharma Staff

Ology Bioservices, a biologics contract development and manufacturing organization (CDMO), said that the Department of Defense (DOD), through the Joint Science and Technology Office of the Defense Threat Reduction Agency (DTRA), has awarded the company with a contract to manufacture a novel live attenuated tularemia vaccine. The contract value is $6.3 million.
 
The vaccine candidate ATI-1701 (F. tularensis ΔclpB) is a novel attenuated version derived from the virulent SCHU S4 strain of tularemia. Appili Therapeutics, an infectious disease-focused biotechnology company, holds the world-wide license of the candidate and serves as the sponsor of the product-candidate. In this program, Ology Bio will manufacture the vaccine candidate under CGMP guidelines and perform a safety assessment using a rabbit model.
 
“Ology Bio is pleased to be working with the DOD and our colleagues at Appili Therapeutics to advance this important new vaccine candidate,” said Peter Khoury, president and chief executive officer, Ology Bio. “Tularemia remains an important biological threat but to date no licensed vaccine exists to protect against this disease.”
 
Armand Balboni, chief executive officer, Appili Therapeutics, said, “ATI-1701 is an important part of our anti-infective pipeline program, and we are very grateful for the continued support from DTRA and our partners at Ology Bio to advance this program for the benefit of civilian and military populations.”

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